Why do pharmaceutical firms disfavor CBD in medical treatments?
4 min read
Cannabidiol, abbreviated as CBD, is a naturally-occurring compound present in the cannabis plant. In contrast to THC (tetrahydrocannabinol), a widely recognized component, CBD does not induce psychoactive effects and does not lead to a sensation of being “high” upon ingestion.
Among the 100-plus cannabinoids identified in the cannabis plant, CBD has garnered increasing attention for its potential health advantages. Typically derived from hemp, a cannabis strain with low THC and high CBD levels, CBD has become popular in recent years.
CBD is thought to exert therapeutic effects on the body’s endocannabinoid system, a regulator of functions such as mood, appetite, sleep, and immune response. Several studies propose that CBD could offer potential advantages for various health conditions, including anxiety, depression, pain, inflammation, and epilepsy.
It’s crucial to highlight that the regulatory status of CBD differs across countries and regions, underscoring the importance of consulting with a healthcare professional before incorporating CBD products into one’s routine.
What sets CBD apart from THC?
CBD (cannabidiol) and THC (tetrahydrocannabinol) are two cannabinoids present in the cannabis plant, each with distinct impacts on the body and mind.
The primary contrast between CBD and THC lies in their psychoactive characteristics. THC is psychoactive, eliciting a “high” sensation upon consumption, whereas CBD is non-psychoactive and does not induce a high.
Here are alternative ways in which CBD and THC exhibit distinctions:
- Legal standing: THC is prohibited in numerous countries and is categorized as a Schedule I substance in the United States. CBD is permitted in various countries and is presently legal in the United States under specific conditions.
- Impact on the body: THC binds to CB1 receptors in the brain and nervous system, leading to effects like euphoria, relaxation, and altered perception. In contrast, CBD does not bind to CB1 receptors and may exert more subtle effects on the body’s endocannabinoid system.
- Medical advantages: THC has been utilized for medical purposes, addressing conditions such as pain, nausea, and muscle spasms. CBD is also thought to offer potential therapeutic benefits and has been investigated for its possible applications in treating anxiety, depression, epilepsy, and other ailments.
- Adverse reactions: THC can result in side effects like dry mouth, red eyes, elevated heart rate, and impaired memory and coordination. On the other hand, CBD is generally considered safe and well-tolerated, but it may lead to side effects such as fatigue, diarrhea, and changes in appetite.
It is crucial to emphasize that the impacts of CBD and THC can vary based on the mode of consumption, dosage, and individual tolerance and sensitivity. Consulting with a healthcare professional before using any cannabis-related products is essential.
Advantages of CBD:
CBD (cannabidiol) is thought to possess numerous potential health advantages, though additional research is required to comprehensively grasp its effects. The following are some of the benefits that have been examined and documented:
- Pain alleviation: CBD exhibits anti-inflammatory properties and has demonstrated potential in relieving pain associated with conditions like arthritis, multiple sclerosis, and chronic pain.
- Anxiety and depression: CBD has been researched for its possible efficacy in addressing anxiety and depression. Through interaction with serotonin receptors in the brain, it may contribute to anxiety reduction and mood improvement.
- Neuroprotective characteristics: CBD has displayed neuroprotective attributes and may offer protection against neurodegenerative diseases such as Alzheimer’s and Parkinson’s.
- Anti-seizure effects: The FDA has sanctioned CBD as a treatment for seizures linked to specific forms of epilepsy.
- Symptoms related to cancer: CBD may assist in alleviating symptoms like nausea, vomiting, and pain associated with cancer and its treatment.
- Acne: With its anti-inflammatory properties, CBD may help mitigate acne.
- Heart health: CBD could potentially aid in reducing high blood pressure and may have beneficial effects on heart health.
What causes pharmaceutical companies to be wary of CBD?
Pharmaceutical companies might perceive CBD (cannabidiol) as a competitor because of its potential as a natural alternative to certain prescription medications. CBD has demonstrated therapeutic effects on various health conditions, and individuals may opt for it over prescription drugs due to potential side effects and risks associated with the latter.
CBD has undergone research for its potential efficacy in addressing conditions like anxiety, depression, pain, inflammation, and epilepsy. Some studies indicate its effectiveness in reducing seizures linked to specific forms of epilepsy, leading to FDA approval for a CBD-based drug, Epidiolex, for seizure treatment.
Concerns within pharmaceutical companies may also stem from the uncertain regulatory status of CBD in certain countries and regions. Ambiguity or ongoing regulatory changes can create instability, making it challenging for pharmaceutical companies to develop and market CBD-based drugs.
Nevertheless, it is important to acknowledge that certain pharmaceutical companies have initiated the development of drugs based on CBD and have integrated CBD into their product portfolios. In fact, collaboration between pharmaceutical companies and cannabis entities for the research and development of novel CBD-based drugs has been observed. Therefore, while some pharmaceutical companies may view CBD as a potential competitor, others might perceive it as an avenue for expansion and innovation.
